中国干眼专家共识：药物相关性干眼（2021年）

眼局部和全身用药均有可能导致药物相关性干眼，已成为干眼的重要病因之一，临床易漏诊、误诊。为引起眼科医师对此类干眼的重视，亚洲干眼协会中国分会等相关学术组织的专家在《干眼临床诊疗专家共识（2013年）》的基础上，结合该领域新的研究进展及临床实践经验，在其名称、定义与分类、危险因素、相关药物种类、发病机制、诊断及鉴别诊断、治疗原则、预防措施等方面形成共识意见，以提高我国药物相关性干眼的规范化诊疗水平。（中华眼科杂志，2021，57：734-742）【关键词】干眼综合征；药物相关性副作用和不良反应；诊疗准则；多数赞同Chinese expert consensus on dry eye:dry eye related to drugs(2021)Chinese Branch of the Asian Dry Eye Society,Ocular Surface and Tear Film diseases Group ofOphthalmologyCommitteeofCross‑StraitsMedicineExchangeAssociation,Ocular Surface and Dry EyeGroup of Chinese Ophthalmologist AssociationCorresponding author:Liu Zuguo,Department of Ophthalmology,Xiang′an Hospital and Xiamen EyeCenter affiliated to Xiamen University,Eye Institute of Xiamen University,Fujian Provincial KeyLaboratory of Ophthalmology and Visual Science,Fujian Engineering and Research Center of EyeRegenerative Medicine,Xiamen361102,China,Email:zuguoliu@xmu.edu.cn【Abstract】Ocularlocalorsystemicmedicationmaycausedrug‑relateddryeye,which hasbecome one of the important types of dry eye.A missed diagnosis or misdiagnosis of this type of dryeye is easy to occur clinically.To arouse the attention of ophthalmologists,experts from the ChineseBranch of the Asian Dry Eye Society and other related academic organizations have combined thenew research progress and clinical practice associated with this specific disease,in terms of itsdefinition,classification,risk factors,related drug types,pathogenesis,diagnosis,differentialdiagnosis,treatment principles and preventive measures,to form expert consensus opinions,hopingto promote the standardized diagnosis and treatment of drug‑related dry eye in China.(Chin JOphthalmol,2021,57:734-742)【Key words】Dry eye syndromes;Drug‑related side effects and adverse reactions;Practice guideline;Consensus在临床工作中，患者个体因素、药物自身因素或药物不合理使用等，可造成部分眼局部或全身药物的应用成为导致干眼的常见原因［1］。2013年中华医学会眼科学分会角膜病学组在其制定的《干眼·标准与规范探讨·DOI：10.3760/cma.j.cn112142-20210726-00350收稿日期2021-07-26本文编辑黄翊彬引用本文：亚洲干眼协会中国分会,海峡两岸医药卫生交流协会眼科学专业委员会眼表与泪液病学组,中国医师协会眼科医师分会眼表与干眼学组.中国干眼专家共识：药物相关性干眼（2021年）[J].中华眼科杂志,2021,57(10):734-742.DOI:10.3760/cma.j.cn112142-20210726-00350.··734